Physiological signal monitoring device

ABSTRACT

A physiological signal monitoring device includes a sensing member and a transmitter connected to the sensing member and including a circuit board that has electrical contacts, and a connecting port, which includes a socket communicated to the circuit board and a plurality of conducting springs. The sensing member is removably inserted into the socket. The conducting springs are electrically connected to the electrical contacts and the sensing member for enabling electric connection therebetween. Each of the conducting springs is frictionally moved by the sensing member during insertion of the sensing member into the socket and removal of the sensing member from the socket.

CROSS-REFERENCE TO RELATED APPLICATION

This application claims priorities of U.S. Provisional PatentApplication No. 62/882,140, filed on Aug. 2, 2019, Taiwanese PatentApplication No. 109109245, filed on Mar. 19, 2020, Taiwanese PatentApplication No. 109100968, filed on Jan. 10, 2020, and Taiwanese PatentApplication No. 109100852, filed on Jan. 10, 2020.

FIELD

The disclosure relates to a sensor, and more particularly to aphysiological signal monitoring device.

BACKGROUND

Referring to FIG. 23 , a conventional sensing device 900 disclosed inU.S. Pat. No. 7,899,511 includes abase 92, an adhesive base 91 that isadapted for adhering the base 92 onto a host's skin (not shown), abiosensor 93 that is mounted in the base 92, and a transducer 94 that ismounted to the base 92 and that is connected to the biosensor 93. Thebiosensor 93 is inserted beneath the host's skin for measuring aphysiological signal corresponding to the blood glucose concentrationlevel, and the transducer 94 receives the physiological signal from thebiosensor 93 and forwards the physiological signal to an external device(not shown).

Furthermore, referring to FIG. 24 , the biosensor 93 includes a fixedseat 931, an elongated sensing member 932 that is fixedly mounted to thefixed seat 931, and two contactor heads 933 that are fixedly mounted tothe fixed seat 931 and that are in contact with the sensing member 932.When the transducer 94 covers the base 92 to be mounted thereto, contactpoints (not shown) at a bottom end of the transducer 94 are to be indirect contact with the contactor heads 933 for enabling electricconnection between the transducer 94 and the sensing member 932.However, as the transducer 94 and the sensing members 932 are spacedapart in a coupling direction while the contactor heads 933 extends inthe same direction for enabling the electric connection therebetween,the thickness of each of the contactor heads 933 (length in the couplingdirection) cannot be smaller than the distance between the transducer 94and the sensing member 932. As such, minimum thickness restriction tothe contactor heads 933 made it difficult to reduce the overallthickness of sensing device 900. In addition, the contactor heads 933may not be able to properly enable electric connection between thebiosensor 93 and the transducer 94 due to manufacturing errors, such asmisalignment of the contactor heads 933, or the contactor heads 933having the thickness different from the distance between the transducer94 and the sensing member 932.

SUMMARY

Therefore, an object of the disclosure is to provide a physiologicalsignal monitoring device that can alleviate the drawbacks of the priorart.

According to the disclosure, the physiological signal monitoring deviceis for sensing a physiological signal in an analyte of a host, andincludes a sensing member and a transmitter. The sensing member includesa signal sensing end adapted to be inserted underneath a skin of thehost to sense the physiological signal, and a signal output end foroutputting the physiological signal. The transmitter is connected to thesensing member for receiving, processing and transmitting thephysiological signal, and includes a circuit board and a connectingport. The circuit board has a plurality of electrical contacts. Theconnecting port is connected to the circuit board and has a socket whichis communicated to the circuit board, and a plurality of conductingsprings which are received within the connecting port. The conductingsprings are disposed at two opposite sides of the socket. The sensingmember is removably inserted into the socket. Each of the conductingsprings has one side electrically connected to a respective one of theelectrical contacts of the circuit board and another side electricallyconnected to the signal output end of the sensing member for electricconnection between the respective one of the electrical contacts and thesignal output end. Each of the conducting springs is frictionallyrotated by the sensing member during insertion of the sensing memberinto the socket and removal of the sensing member from the socket.

BRIEF DESCRIPTION OF THE DRAWINGS

Other features and advantages of the disclosure will become apparent inthe following detailed description of the embodiment with reference tothe accompanying drawings, of which:

FIG. 1 is a perspective view of a first embodiment of a physiologicalsignal monitoring device according to the disclosure;

FIG. 2 is an exploded perspective view of the first embodiment;

FIG. 3 is an exploded perspective view of a transmitter of the firstembodiment;

FIG. 4 is a partly exploded perspective view of a bottom casing and aconnecting port of the transmitter of a modification the firstembodiment;

FIG. 5 is a fragmentary and enlarged perspective view of the connectingport in FIG. 4 ;

FIG. 6 is a fragmentary sectional view taken along line VI-VI in FIG. 1;

FIG. 7 is a cutaway perspective view of the first embodiment;

FIG. 8 is a fragmentary sectional view of another modification of thefirst embodiment;

FIG. 9 is a fragmentary sectional view of yet another modification ofthe first embodiment;

FIGS. 10 and 11 circuit diagrams of the first embodiment, respectivelyillustrating the transmitter before and after being coupled to abiosensor;

FIGS. 12 to 14 are circuit diagrams of various modifications of asensing member and a connecting port of the first embodiment;

FIG. 15 is a fragmentary sectional view of a second embodiment of thephysiological signal monitoring device;

FIG. 16 is an enlarged view of FIG. 15 ;

FIG. 17 is an enlarged fragmentary sectional view of a third embodimentof the physiological signal monitoring device;

FIG. 18 is an enlarged fragmentary sectional view of a fourth embodimentof the physiological signal monitoring device;

FIGS. 19 and 20 are enlarged fragmentary sectional views of variousmodifications of the fourth embodiment;

FIG. 21 is a fragmentary sectional view of still another modification ofthe first embodiment;

FIG. 22 is a fragmentary sectional view of a modification of the secondembodiment;

FIG. 23 is an exploded perspective view of a conventional sensingdevice; and

FIG. 24 is an exploded perspective view of a biosensor of theconventional sensing device.

DETAILED DESCRIPTION

Before the disclosure is described in greater detail, it should be notedthat where considered appropriate, reference numerals or terminalportions of reference numerals have been repeated among the figures toindicate corresponding or analogous elements, which may optionally havesimilar characteristics.

In addition, in the description of the disclosure, the terms “up”,“down”, “top”, “bottom” are meant to indicate relative position betweenthe elements of the disclosure, and are not meant to indicate the actualposition of each of the elements in actual implementations. Similarly,various axes to be disclosed herein, while defined to be perpendicularto one another in the disclosure, may not be necessarily perpendicularin actual implementation.

Referring to FIGS. 1 to 7 , a first embodiment of the physiologicalsignal monitoring device according to the disclosure is adapted to bemounted to a skin surface of a host (not shown), and is adapted formeasuring at least one analyte of the host and for sending acorresponding type of physiological signal. In this embodiment, thephysiological signal monitoring device is for measuring the bloodglucose concentration in the interstitial fluid (ISF) of the host, andis meant to be mounted to the skin surface for two weeks, but is notrestricted to such.

Referring back to FIGS. 1 and 2 , the physiological signal monitoringdevice includes a base 1 that is adapted to be mounted to the skinsurface of the host, a biosensor 2 that is mounted to the base 1 andthat is adapted to be partially inserted underneath the skin surface ofthe host, and a transmitter 3 that covers and is removably coupled tothe base 1 in a direction of a first axis (D1) and that is connected tothe biosensor 2. The biosensor 2 is adapted for measuring at least oneanalyte of the host and for sending a corresponding physiological signalto the transmitter 3, while the transmitter 3 receives, processes, andoutputs the physiological signal to an external device (not shown) formonitoring purposes. When the physiological signal monitoring device isto be replaced after a prolonged period of use, the transmitter 3 ispermitted to be separated from the biosensor 2 and the base 1 to bereused with a new set of the base 1 and biosensor 2.

The base 1 includes a base body 11, and an adhesive pad 16 that ismounted to a bottom surface 116 (see FIG. 6 ) of the base body 11 andthat is permitted for attaching the base body 11 to the skin surface ofthe host. The biosensor 2 includes a fixed seat 21 that is mounted tothe base body 11, and a sensing member 22 that is mounted to the fixedseat 21 and that extends through the base body 11. The fixed seat 21 ismounted between the transmitter 3 and the base 1 when the transmitter 3is coupled to the base 1.

The fixed seat 21 has a bottom surface 211 and a top surface 212. Thesensing member 22 has a signal sensing end 222 that is adapted to beinserted underneath the skin surface of the host for measuring thephysiological signal of the host, and a signal output end 221 that isadapted to output the physiological signal received from the signalsensing end 222. The signal sensing end 222 protrudes from the bottomsurface 211 of the fixed seat 21, and the signal output end 221protrudes from the top surface 212 of the fixed seat 21.

Referring to FIGS. 2 and 11 , the sensing member 22 includes a baseboard 225, a plurality of electrodes 226 mounted to a surface of thebase board 225, and an analyte sensing layer (not shown) that covers theelectrodes 226 and the surface of the base board 225. The analytesensing layer is provided for reacting with the at least one analyte ofthe host, and the electrodes 226 includes signal receiving electrodesthat detect outcome of the reaction, and signal sending electrodes thatgenerate an electric signal indicating the outcome of the reaction. Inthis embodiment, the electric signal is the physiological signal thatindicates glucose levels in the interstitial fluid. Specific roles ofthe electrodes 226 will be elaborated later.

Referring back to FIGS. 2, 3 and 6 , the transmitter 3 includes a bottomcasing 31 that is proximate to the base body 11, a top casing 32 that ismounted to the bottom casing 31 to define an inner space 30, a circuitboard 33 that is disposed in the inner space 30, a processing unit 34(see FIGS. 10 and 11 ) that is mounted to the circuit board 33, abattery 35 that is disposed in the inner space 30, and a connecting port36 that is connected to a bottom surface of the circuit board 33 andthat extends outwardly from the inner space 30 toward the base body 11.

The circuit board 33 is permitted to be printed circuit board (PCB) orflexible print circuit (FPC), and is fixedly positioned to the bottomcasing 31 via a supporting member 37, which may be made of a metalplate. The circuit board 33 has a plurality of electrical contacts 331that correspond in position to the connecting port 36. In thisembodiment, the number of the electrical contacts 331 is eight. Theprocessing unit 34 is provided for receiving, processing, and sendingthe physiological signal, and is connected to the electrical contacts331. The battery 35 is connected to the electrical contacts 331 of thecircuit board 33.

Referring back to FIGS. 3, 6 and 7 , the connecting port 36 includes aport casing 361 that is mounted to a bottom surface of the circuit board33 and that extends downwardly toward a bottom surface 311 of the bottomcasing 31 in the direction of the first axis (D1), and a plurality ofspaced-apart conducting members 364 that are received within the portcasing 361. In this embodiment, the number of the conducting members 364is eight.

The port casing 361 is formed with a plurality of grooves 366 opentoward the circuit board 33 and respectively receiving the conductingmembers 364 therein, and a socket 367 that extends toward the base body11 in the direction of the first axis (D1) and that is communicated tothe grooves 366. The conducting members 364 are respectively androtatably received within the grooves 366. The socket 367 is provided tohold the signal output end 221 of the sensing member 22.

Referring back to FIGS. 4 and 5 , in a modification of the firstembodiment, a cross section of an outer periphery of the grooves 336perpendicular to the first axis (D1) is substantially dovetail-shaped,and each of the grooves 336 tapers toward the socket 367 for preventingeach of the conducting members 364 from escaping the respective one ofthe grooves 336.

The conducting members 364 are elastic, and are disposed at two oppositesides of the socket 367. In this embodiment, the conducting members 364are conducting coil springs. Each of the conducting members 364 contactswith the circuit board 33 at one side along with a first direction, andcontacts with the sensing member 22 at another side along a seconddirection wherein the first direction is nonparallel to the seconddirection. Therefore, the electric connection between the electricalcontacts 331 of the circuit board 33 and the signal output end 221 ofthe sensing member 22 is provide when the sensing member 22 is insertedinto the socket 367. Specifically, each of the conducting members 364has one side that is in contact with (and electrically connected to) arespective one of the electrical contacts 331 of the circuit board 33 inthe direction of the first axis (D1) (i.e., the first direction) andanother side that is in contact with (and electrically connected to) theelectrodes 226 on the signal output end 221 of the sensing member 22 ina direction of a second axis (D2) (i.e., the second direction) forpositioning the sensing member 22 when it is inserted into the socket367 and for enabling electric connection between the electrical contacts331 of the circuit board 33 and the signal output end 221 of the sensingmember 22. In this embodiment, the first and second axes (D1, D2) aresubstantially perpendicular to each other, but may not be restricted assuch in other embodiments. The conducting coil springs have high degreesof freedom such that each of the conducting members 364 is rotatedrelative to the grooves 366 during insertion of the sensing member 22into the socket 367 and removal of the sensing member 22 from the socket367 along the first axis (D1), thereby reducing friction between thesocket 367 and the sensing member 22 and facilitating the reuse of thetransmitter 3.

It should be noted that, in this embodiment, each of the conductingmembers 364 has one end welded to the port casing 361 so that one end ofeach of the conducting members 364 is fixed on the respective one of thegrooves 366. In addition, as the conducting members 364 are conductingcoil springs, each of the conducting members 364 has the followingproperties: the wire diameter thereof is smaller than 1 millimeter (mm),preferably 0.1 mm; the outer diameter thereof ranges from 0.5 mm to 1.8mm, preferably 1.1 mm; the free length thereof ranges from 0.2 mm to 0.8mm, preferably 0.44 mm to 0.56 mm. Each of the conducting members 364has a helical portion 365 a with two to six turns (three turns in thisembodiment), thereby providing multi-point contacts with the respectiveone of the electrical contacts 331 of the circuit board 33 and thesignal output end 221 of the sensing member 22. It should be noted that,parameters such as the wire diameter and the number of turns of each ofthe conducting members 364 are designed in consideration to theelasticity of the conducting members 364, and the outer diameter and thefree length of each of the conducting members 364 are designed in such away that each of the conducting members 364 is slightly larger than aspace of the respective one of the grooves 366, so that the conductingmembers 364 are in stable contact with the electrical contacts 331 ofthe circuit board 33 and the electrodes 226 on the signal output end 221of the sensing member 22 (see FIGS. 2 and 11 ).

Referring to FIG. 8 , in another modification of the first embodiment,the conducting members 364 of the connecting port 36, which wereoriginally conductive coil springs in the first embodiment, are steelballs or steel rings (i.e., rigid components) instead. In addition, theconnecting port 36 further includes a plurality of elastic members 369,each of which is mounted in the respective one of the grooves 366 and ismounted between the port casing 361 and a respective one of theconducting members 364. The elastic members 369 are made of elasticmaterials such as rubber, and each of the conducting members 364 has oneside contacted with the respective elastic member 369 and another sidecontacted with the electrodes 226 of the the signal output end 221 alongan axis parallel to the second axis (D2). Overall, the conductingmembers 364 in this modification functions similarly to that of thefirst embodiment: enabling electric connection between the electricalcontacts 331 and the signal output end 221, and being frictionally movedby the sensing member 22 to rotate in the grooves 366. The elasticmembers 369 ensure that the conducting members 364 are in stable contactwith the sensing member 22 and the circuit board 33 along the directionsparallel to the first axis (D1) and the second axis (D2) respectively.

Referring to FIG. 9 , in yet another modification of the firstembodiment, the conducting members 364 are conducting coil strings, eachof which has an extended section 365 b that extends along an innersurface of the port casing 361 toward the circuit board 33, and that isconnected to the respective one of the electrical contacts 331 in thedirection of the first axis (D1).

Referring to FIGS. 10 and 11 , in the first embodiment, the processingunit 34 receives the electric signal from the sensing member 22 andsends a corresponding physiological signal. The processing unit 34includes a signal amplifier 341 receiving and amplifying the electricsignal, a measuring and computing module 342 that converts the amplifiedelectric signal sequentially into a physiological signal correspondingto the glucose level, and a transmitting module 343 that sends thephysiological digital signal to an external device (not shown) via anantenna 344. It should be noted that, in the disclosure, theabovementioned physiological signal corresponding to the glucose levelis electric current.

As previously mentioned, the number of the conducting members 364 iseight in this embodiment. The conducting members 364 are conducting coilsprings and include two power-supplying conducting members 364 a, foursensing conducting members 364 b, and two transmitting conductingmembers 364 c. The electrodes 226 of the sensing member 22 are incontact with the conducting members 364 to be respectively andelectrically connected to the electrical contacts 331 of the circuitboard 33 for the purposes of supplying power, sensing and transmittingdata.

The power-supplying conducting members 364 a and the electrodes 226cooperatively forma switch. The sensing conducting members 364 b areconnected to the processing unit 34. The transmitting conducting members364 c are connected to the processing unit 34 as well, and transmit datato the external device via the transmitting module 343 and the antenna344. In this embodiment, type of data transmission may be wirelesstransmission (Bluetooth, Wifi, NFC), but may be wired transmission (USBcable) in other embodiments.

In this embodiment, the number of the electrodes 226 of the sensingmember 22 is five. The electrodes 226 include a working electrode 226 a,a reference electrode 226 b, a power-supplying electrode 226 e, and twoelectrical contact sections 226 d.

When the sensing member 22 is not inserted into the socket 367 of theconnecting port 36, the switch formed by the conducting members 364 a isin an open circuit state, so that the battery 35 is in a non-powersupplying state.

When the sensing member 22 is inserted into the socket 367, thepower-supplying electrode 226 e of the sensing member 22 is in contactwith the power-supplying conducting members 364 a to be electricallyconnected with the electrical contacts 331 of the circuit board 33, suchthat the switch is in a closed circuit state and the battery 35 isswitched to a power supplying state for supplying power to the sensingmember 22 and the processing unit 34 for performing measurement of theanalyte. At the same time, each of the working and reference electrode226 a, 226 b is in contact with corresponding two of the sensingconducting members 364 b to be electrically connected to the electricalcontacts 331 of the circuit board 33, such that the processing unit 34receives, processes, and sends the physiological signal to the externaldevice. The electrical contact sections 226 d are permitted to berespectively and electrically connected to the transmitting conductingmembers 364 c. In this embodiment, the electrical contact sections 226 dhas signal receiving and signal sending electrodes.

A circuit layout of the transmitter 3 can be modified according to thevarious requirement of the product. For example, referring to FIG. 12 ,the sensing member 22 begins measurement of the physiological signal ofthe host without power control by the processing unit 34 when thesensing member 22 is inserted into the socket 367. The circuitconcerning to the power supply can be rearranged in other embodiments,so there is no more detailed description herein.

In addition, the socket 367 of the connecting port 36 is further adaptedfor additional transmission device (not shown) or charging device (notshown) to be inserted thereinto. For example, after the transmitter 3 ismanufactured (before being connected to the biosensor 2 and the base 1),a connector (or an electrode) of the additional transmission device maybe inserted into the socket 367 to provide electric connection and datatransmission between the processing unit 34 and the additionaltransmission device through the transmitting conducting members 364 c.In other words, in this embodiment, the transmitting conducting members364 c are permitted to be electrically connected to the additionaltransmission device for exchanging data (default data or calibrationdata) before the transmitter 3 is connected to the biosensor 2 and thebase 1. Furthermore, when the transmitter 3 is uncoupled from thebiosensor and the base 1 for repeated use, the charging device may beinserted into the socket 367 to recharge the transmitter 3 through thepower-supplying conducting members 364 a, which electricallyinterconnect the electrical contacts 331 of the circuit board 33 and thecharging device.

Referring to FIG. 13 , in another modification of the sensing member 22and the socket 36 of the first embodiment, the electrodes 226 of thesensing member 22 include a working electrode 226 a, a counter electrode226 f, a power-supplying electrode 226 e, and two electrical contactsections 226 d, and the number of the conducting members 364 of thetransmitter 3 is six. The conducting members 364 are conducting coilsprings and include two power-supplying conducting members 364 a, twosensing conducting members 364 b, and two transmitting conductingmembers 364 c. When the sensing member 22 is inserted into the socket367 of the connecting port 36, the power-supplying electrode 226 e ofthe sensing member 22 is in contact with the power-supplying conductingmembers 364 a to be electrically connected with the electrical contacts331 of the circuit board 33. At the same time, each of the working andcounter electrode 226 a, 226 f is in contact with a respective one ofthe sensing conducting members 364 b to be electrically connected to theelectrical contacts 331 of the circuit board 33, such that theprocessing unit 34 receives, processes, and sends the physiologicalsignal to the external device. The electrical contact sections 226 d arepermitted to be respectively and electrically connected to thetransmitting conducting members 364 c.

Referring to FIG. 14 , in yet another modification of the sensing member22 and the socket 36 of the first embodiment, the electrodes 226 of thesensing member 22 include a working electrode 226 a, a counter electrode226 f, and two power-supplying electrodes 226 e, and the number of theconducting members 364 of the transmitter 3 is four. The conductingmembers 364 are conducting coil springs and include two power-supplyingconducting members 364 a and two sensing conducting members 364 b. Whenthe sensing member 22 is inserted into the socket 367 of the connectingport 36, the power-supplying electrodes 226 e of the sensing member 22are respectively in contact with the power-supplying conducting members364 a to be electrically connected with the electrical contacts 331 ofthe circuit board 33. At the same time, each of the working and counterelectrode 226 a, 226 f is in contact with a respective one of thesensing conducting members 364 b to be electrically connected to theelectrical contacts 331 of the circuit board 33, such that theprocessing unit 34 receives, processes, and sends the physiologicalsignal to the external device.

By utilizing the abovementioned modifications of the sensing member 22and the socket 36 of the first embodiment, the electrical contacts 331of the circuit board 33 and the electrodes 226 of the sensing member 22are able to be electrically connected to activate the processing unit34. It should be noted that the conducting coil springs in theabovementioned modifications may be conducting components of otherforms.

In the above embodiments, the transmitter 3 is coupled to the biosensor2 assembled on the base 1 wherein the base 1 is attached on the hostskin. Accordingly, the sensing member 22 of the biosensor 2 is insertedinto the socket 367 of the transmitter 3 for the measurement of theanalyte.

Overall, the first embodiment of the physiological signal monitoringdevice provides the following benefits:

1) The sensing member 22 is inserted into the transmitter 3 wherein eachof the conducting members 364 bidirectionally contacts with theelectrodes 226 of the sensing member 22 and the electrical contacts 331of the circuit board 33 along directions of the first axis (D1) and thesecond axis (D2) respectively. Therefore, the sensing member 22 isstably held within the socket 367 by the elastic conducting members 364to provide reliable electric connection and signal transmission betweenthe circuit board 33 and the sensing member 22.

2) In addition, the conducting members 364 could be the elastic coilconducting springs or the steel members complemented by the elasticmembers 369 to raise the tightness between the sensing member 22 and thecircuit board 33 such that the reliable electric connection and signaltransmission is provided. Due to the complementary assembly between thesensing member 22 and the socket 367, the vertical size of the devicecould be reduced. Furthermore, in this embodiment, because theconducting members 364 have high degree of freedom in the grooves 366,each of the conducting members 364 is forced to rotate relative to thegrooves 366 during insertion of the sensing member 22 into the socket367 and removal of the sensing member 22 from the socket 367, therebyreducing friction resistance between the socket 367 and the sensingmember 22 and facilitating the reuse of the transmitter 3.

3) The battery 35 has not been turned on until the sensing member 22 isinserted into the socket 367 of the connecting port 36, therebypreventing from the power consumption before activating thephysiological signal monitoring device. In addition, the socket 367 maybe further adapted for the additional transmission device or a chargingdevice to be inserted thereinto for data transmission and power chargingrespectively. Specifically, the power-supplying electrode of thecharging device could be electrically connected with the electricalcontacts 331 of the circuit board 33 through the power-supplyingconducting members 364 a for power charging; the electrical contactsections 226 d of the additional transmission device could beelectrically connected with the electrical contacts 331 of the circuitboard 33 through the transmitting conducting members 364 c for datatransmission.

FIGS. 15 and 16 illustrate a second embodiment of the physiologicalsignal monitoring device wherein the difference between the firstembodiment and the second embodiment is described as follows.

The port casing 361 of the connecting port 36 has a plurality of slantedsurfaces 368 respectively disposed in the grooves 366 and facing thecircuit board 33 and the sensing member 22. Therefore, the conductingmembers 364 are forced against the circuit board 33 and the sensingmember 22 with force vector provided by the slanted surfaces 368 toensure the contact therebetween and enhance the mobility of theconducting members 364. Moreover, the conducting members 364 couldreturn to the predetermined position after the removal of the sensingmember 22 from the socket 367 because of the slanted surfaces 368 suchthat the contact problem resulting in electric disconnection between theconducting member 364 and the sensing member 22 could be solved. Inother embodiments, the conducting members 364 could be modified as hardcomponents (ex. steel ball or steel ring) with the elastic members 369configured between the conducting members 364 and the slanted surfaces368.

FIG. 17 illustrates a third embodiment of the physiological signalmonitoring device wherein the difference between the first embodimentand the third embodiment is described as follows.

In this embodiment, each of the conducting members 364 of the connectingport 36 is a leaf spring with one end contacted with the correspondingelectrical contact 331 of the circuit board 33 along the first axis (D1)and another end contacted with the electrodes 226 of the sensing member22 along the second axis (D2). Accordingly, the sensing member 22 isstably held within the socket 367 by the leaf springs 364 to providereliable electric connection and signal transmission between the circuitboard 33 and the sensing member 22.

FIG. 18 illustrates a fourth embodiment of the physiological signalmonitoring device wherein the difference between the first embodimentand the fourth embodiment is described as follows.

The conducting members 364 are conducting coil springs. The connectingport 36 further includes a plurality of metal plates 370 respectivelyconnected to the electrical contacts 331. In this embodiment, the metalplates 370 are welded to the electrical contacts 331 via surface mounttechnology (SMT), and extended toward the grooves 366 to be disposedbetween the port casing 361 and the conducting members 364. Therefore,each of the conducting members 364 coaxially contacted with a respectiveone of the metal plates 370 and the electrodes 226 of the sensing member22 along an axis parallel to the second axis (D2) to provide reliableelectric connection between the circuit board 33 and the sensing member22.

FIGS. 19 and 20 illustrate other modifications of the fourth embodiment,in which the conducting members 364 are steel balls or steel ringsinstead wherein the metal plates 370 are welded to the electricalcontacts 331 via surface mount technology (SMT) shown as FIG. 19 or dualin-line package (DIP) shown as FIG. 20 .

It should be noted that in the abovementioned embodiments, theconducting members 364 of the connecting port 36 are disposed at twoopposite sides of the socket 367. However, in other embodiments, theconducting members 364 of the connecting port 36 can be disposed atsingle side of the socket 367 instead, such that only single side of thesensing member 22 is abutted against the conducting members 364.Referring to FIGS. 21 and 22 , the sensing member 22 is stably heldwithin the socket 367 by the elastic conducting members 364 and the portcasing 361 to provide reliable electric connection between the circuitboard 33 and the sensing member 22.

Consequently, the conducting members 364 are laterally configured at thesocket 367 to contact with the electrodes 226 of the sensing member 22and the electrical contacts 331 of the circuit board 33 after thetransmitter 3 is coupled to the biosensor 2, thereby providing thereliable electric connection therebetween and holding of the sensingmember 22. Moreover, the conducting members 364 are rotated relative tothe grooves 366 during insertion or removal of the sensing member 22from the socket 367 to reduce friction resistance between conductingmembers 364 and the sensing member 22 and facilitate the reuse of thetransmitter 3. In addition, the conducting members 364 can be conductingcoil springs, steel balls/rings with the elastic members 369 or metalplates 370 to provide bidirectional or coaxial connection between thesensing member 22 and the circuit board 33. Therefore, the electrodes226 of various functions are electrically connected with the electricalcontacts 331 of single connecting port 36 to activate the power supply,signal sensing and date transmission.

In addition to the embodiments described above, this disclosure furtherdiscloses a plurality of embodiments as defined by the claims, with eachembodiment comprising the claim element(s) of the respective claim andthe claim element(s) of any claim upon which the respective claimdepends.

In the description above, for the purposes of explanation, numerousspecific details have been set forth in order to provide a thoroughunderstanding of the embodiment. It will be apparent, however, to oneskilled in the art, that one or more other embodiments may be practicedwithout some of these specific details. It should also be appreciatedthat reference throughout this specification to “one embodiment,” “anembodiment,” an embodiment with an indication of an ordinal number andso forth means that a particular feature, structure, or characteristicmay be included in the practice of the disclosure. It should be furtherappreciated that in the description, various features are sometimesgrouped together in a single embodiment, figure, or description thereoffor the purpose of streamlining the disclosure and aiding in theunderstanding of various inventive aspects, and that one or morefeatures or specific details from one embodiment may be practicedtogether with one or more features or specific details from anotherembodiment, where appropriate, in the practice of the disclosure.

While the disclosure has been described in connection with what isconsidered the exemplary embodiment, it is understood that thisdisclosure is not limited to the disclosed embodiment but is intended tocover various arrangements included within the spirit and scope of thebroadest interpretation so as to encompass all such modifications andequivalent arrangements.

What is claimed is:
 1. A physiological signal monitoring device forsensing a physiological signal in an analyte of a host, comprising: asensing member, including a signal sensing end adapted to be insertedunderneath a skin of the host to sense the physiological signal, and asignal output end for outputting the physiological signal; and atransmitter connected to said sensing member for receiving, processingand transmitting the physiological signal, and including a circuit boardhaving a plurality of electrical contacts, and a connecting portconnected to said circuit board and having a socket which iscommunicated to said circuit board, and a plurality of conductingsprings which are received within said connecting port; wherein saidsensing member is removably inserted into said socket; wherein each ofsaid conducting springs has one side electrically connected to arespective one of said electrical contacts of said circuit board andanother side electrically connected to said signal output end of saidsensing member for electric connection between the respective one ofsaid electrical contacts and said signal output end; and wherein saidconducting springs are frictionally rotated by said sensing memberduring insertion of said sensing member into said socket and removal ofsaid sensing member from said socket.
 2. The physiological signalmonitoring device as claimed in claim 1, wherein said connecting portfurther includes a port casing mounted on said circuit board and formedwith said socket, wherein said port casing has a plurality of slantedsurfaces facing said circuit board and said sensing member therebyforcing said conducting springs against said circuit board and saidsensing members.
 3. The physiological signal monitoring device asclaimed in claim 1, wherein said connecting port further includes a portcasing mounted on said circuit board and formed with said socket, and aplurality of grooves communicated to said socket to receive saidconducting springs therein.
 4. The physiological signal monitoringdevice as claimed in claim 3, wherein each of said grooves of saidconnecting port tapers toward said socket.
 5. The physiological signalmonitoring device as claimed in claim 3, wherein said conducting springsof said connecting port are disposed at one side of said socket.
 6. Thephysiological signal monitoring device as claimed in claim 3, whereinsaid conducting springs of said connecting port are disposed at twoopposite sides of said socket.
 7. The physiological signal monitoringdevice as claimed in claim 3, wherein each of said conducting springshas an extended section extending along an inner surface of said portcasing toward said circuit board and connected to the respective one ofsaid electrical contacts.
 8. The physiological signal monitoring deviceas claimed in claim 3, wherein each of said conducting springs has oneend fixed on a respective one of said grooves.
 9. The physiologicalsignal monitoring device as claimed in claim 1, wherein each of saidconducting springs has said one side contacted with the respective oneof said electrical contacts along a direction of a first axis and saidanother side contacted with said signal output end along a direction ofa second axis.
 10. The physiological signal monitoring device as claimedin claim 1, wherein said connecting port further includes a plurality ofmetal plates respectively connected to said electrical contacts to forcesaid conducting springs against said sensing member, each of saidconducting springs coaxially contacted with a respective one of saidmetal plates and said signal output end of said sensing member.
 11. Thephysiological signal monitoring device as claimed in claim 1, wherein:said sensing member has a plurality of electrodes in contact with saidconducting springs, and including a power-supplying electrode and anelectrode selected from the group consisting of working electrode,reference electrode, and counter electrode and combinations thereof; andsaid conducting springs include sensing conducting springs andpower-supplying conducting springs.
 12. The physiological signalmonitoring device as claimed in claim 11, wherein said conductingsprings further includes a plurality of transmitting conducting springs.13. The physiological signal monitoring device as claimed in claim 11,wherein: said transmitter further includes a battery connected to saidelectrical contacts through said power-supplying conducting springs,said electrodes and power-supplying conducting springs forming a switch;said switch is in an open circuit state, and said battery is in anon-power supplying state when said sensing member is not inserted intosaid socket of said connecting port; and said switch is in a closedcircuit state, and said battery is in a power supplying state when saidsensing member is inserted into said socket of said connecting port toprovide an electric connection between said power-supplying electrode ofsaid sensing member and said power-supplying conducting springs.
 14. Thephysiological signal monitoring device as claimed in claim 11, wherein:said transmitter further includes a processing unit connected to saidelectrical contacts; and at least one of said working, reference andcounter electrodes is in contact with said sensing conducting springsfor transferring the physiological signal to said processing unit whensaid sensing member is inserted into said socket of said connectingport.
 15. The physiological signal monitoring device as claimed in claim12, wherein: said transmitter further includes a processing unitconnected to said electrical contacts; and said socket of saidconnecting port is further adapted for an additional transmission deviceto be inserted thereinto to provide electric connection and datatransmission between said processing unit and said additionaltransmission device through said transmitting conducting springs. 16.The physiological signal monitoring device as claimed in claim 1,wherein each of said conducting springs includes a helical portion witha plurality of turns thereby providing multi-point contacts with therespective one of said electrical contacts of said circuit board andsaid signal output end of said sensing member.
 17. The physiologicalsignal monitoring device as claimed in claim 1, wherein said conductingsprings are leaf springs.
 18. The physiological signal monitoring deviceas claimed in claim 1, wherein said sensing member is inserted into saidsocket along a first axis, and said signal output end of said sensingmember is electrically connected to each of said conducting membersalong a second axis.
 19. The physiological signal monitoring device asclaimed in claim 1, further comprising a fixed seat, wherein the sensingmember is held within the fixed seat.
 20. The physiological signalmonitoring device as claimed in claim 19, further comprising a base thatis removably coupled to said transmitter, wherein said fixed seat ismounted between said transmitter and said base, and said signal sensingend of said sensing member protrudes from a bottom surface of said fixedseat.